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Recombinant Protein >
Recombinant Mouse Cd52 protein, Fc-taggedBrand |
Leading Biology | Catalog Number |
PM0190M1 |
Product Type |
Recombinant Protein | Field of Research |
Cancer Immunotherapy |
Product Overview |
Recombinant Mouse Cd52(Met1-Lys46) fused with Fc region of human IgG1 at C-terminal was expressed in HEK293.
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Protein Length |
Met1-Lys46
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Expression Host |
HEK293
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Species |
Mouse
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Tags |
Fc
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Molecular Weight |
The recombinant mouse Cd52 consists 261 amino acids and predicts a molecular mass of 29 kDa.
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Endotoxin |
<1.0 EU per μg protein as determined by the LAL method.
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Gene Name |
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Symbol |
Cd52
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GeneID |
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mRNA Refseq |
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Protein Refseq |
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UniProt ID |
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Pathway |
Macrophage markers, organism-specific biosystem
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Form |
Lyophilized from sterile PBS, pH 7.4.
Please contact us for any concerns or special requirements.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA. |
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Purity |
> 95 % as determined by SDS-PAGE. |
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Storage & Stability |
Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Samples are stable for up to twelve months from date of receipt at -70 centigrade
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Product Description |
CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.
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Synonyms |
AI463198 Protein, Mouse; B7 Protein, Mouse; B7-Ag Protein, Mouse; CAMPATH-1 Protein, Mouse; CLS1 Protein, Mouse; MB7 Protein, Mouse
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References |
Piccaluga PP, et al. (2007) Expression of CD52 in peripheral T-cell lymphoma. Haematologica. 92(4): 566-7.
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Images |
PM0190M1 |
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Quantity |
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