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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Recombinant Mouse Cd52 protein, Fc-tagged

Recombinant Mouse Cd52 protein, Fc-tagged

PM0190M1
Catalog # Availability Size / Price Inquiry
PM0190M1-20 ug 20 ug / $495
PM0190M1-100 ug 100 ug / $795

Recombinant Mouse Cd52 protein, Fc-tagged

Brand

Leading Biology

Catalog Number

PM0190M1

Product Type

Recombinant Protein

Field of Research

Cancer Immunotherapy

Product Overview

Recombinant Mouse Cd52(Met1-Lys46) fused with Fc region of human IgG1 at C-terminal was expressed in HEK293.

Protein Length

Met1-Lys46

Expression Host

HEK293

Species

Mouse

Tags

Fc

Molecular Weight

The recombinant mouse Cd52 consists 261 amino acids and predicts a molecular mass of 29 kDa.

Endotoxin

<1.0 EU per μg protein as determined by the LAL method.

Gene Name

Symbol

Cd52

GeneID

mRNA Refseq

Protein Refseq

UniProt ID

Pathway

Macrophage markers, organism-specific biosystem

Form

Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

Purity

> 95 % as determined by SDS-PAGE.

Storage & Stability

Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -70 centigrade

Product Description

CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.

Synonyms

AI463198 Protein, Mouse; B7 Protein, Mouse; B7-Ag Protein, Mouse; CAMPATH-1 Protein, Mouse; CLS1 Protein, Mouse; MB7 Protein, Mouse

References

Piccaluga PP, et al. (2007) Expression of CD52 in peripheral T-cell lymphoma. Haematologica. 92(4): 566-7.

Images

PM0190M1

Quantity

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