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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Acetylated Antibodies > Acetyl-DNMT1-K1127/K1129/K1131/K1133 pAb

Acetyl-DNMT1-K1127/K1129/K1131/K1133 pAb

Catalog # Availability Size / Price Inquiry
AMR00748N-1 50ul / $395
AMR00748N-2 100ul / $495
AMR00748N-3 200ul / $595

Acetyl-DNMT1-K1127/K1129/K1131/K1133 pAb

Brand

Leading Biology

Catalog Number

AMR00748N

Product Type

Acetylated Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Epigenetic writers and erasers of core Histones

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Acetyl-DNMT1-K1127/K1129/K1131/K1133 pAb.

Molecular Weight

Calculated MW: 144kDa/183kDa/184kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human DNMT1

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

IHC,IF

Dilution

IHC 1:50 - 1:100 IF 1:50 - 1:100

Product Description

This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.

Synonyms

DNMT1; ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI; DNA methyltransferase 1

Images

Immunofluorescence analysis of C6 cells using Acetyl-DNMT1-K1127/K1129/K1131/K1133 antibody.

Specification

Quantity

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