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Ataxin 3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19588N-1 50ul / $395
APR19588N-2 100ul / $495
APR19588N-3 200ul / $595

Ataxin 3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19588N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Neurodegenerative Diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Ataxin 3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 20kDa/35kDa/39kDa/41kDa Observed MW: 50kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human Ataxin 3 (NP_004984.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Synonyms

ATXN3; AT3; ATX3; JOS; MJD; MJD1; SCA3; ataxin-3

Images

Western blot analysis of extracts of various cell lines, using Ataxin 3 antibody.

Immunofluorescence analysis of HeLa cells using Ataxin 3 antibody.

Specification

Quantity

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