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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Human CSF-1 Protein(C-His Tag)

Recombinant Human CSF-1 Protein(C-His Tag)

PH0067M1
Catalog # Availability Size / Price Inquiry
PH0067M1-20μg 20μg / $325
PH0067M1-100μg 100μg / $955

Recombinant Human CSF-1 Protein(C-His Tag)

Brand

Leading Biology

Catalog Number

PH0067M1

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

Mammalian cell

Species

Human

AA Sequence

P09603-1(Met 1-Asn 190)

Tags

C-His

Molecular Weight

30KD

Activity

Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cells.

Form

lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered PBS, pH7.4

Product Description

M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.

Synonyms

M-CSF Protein(Human); MCSF Protein(Human)

Images

Quantity

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