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Recombinant Human CCL16 Protein(N-His Tag)Brand |
Leading Biology | Catalog Number |
PH0062E3 |
Product Type |
Cytokine | Field of Research |
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Nature |
Recombinant Protein
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Expression Host |
E.coli
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Species |
Human
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AA Sequence |
NP_004581.1(Gln24-Gln120)
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Tags |
N-His
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Molecular Weight |
15KD
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Activity |
Measured by its ability to chemoattract THP?1 human acute monocytic leukemia cells.
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Form |
lyophilized |
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Purity |
Greater than 95% by SDS-PAGE |
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Storage & Stability |
-70°C
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Storage Buffer |
0.2 μm filtered PBS, pH7.4
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Product Description |
Chemokine (C-C motif) ligand 16 (CCL16) is a small cytokine belonging to the CC chemokine family that is known under several pseudonyms, including Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1). This chemokine is expressed by the liver, thymus, and spleen and is chemoattractive for monocytes and lymphocytes. Cellular expression of CCL16 can be strongly induced in monocytes by IL-10, IFN-γ and bacterial lipopolysaccharide. Its gene is located on chromosome 17, in humans, among a cluster of other CC chemokines. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. C-C motif chemokine ligand 16 has been found in high levels in the blood plasma of humans. CCL16 may be useful for trafficking eosinophils. This ligand has been found to have a functional affinity for H4 receptors that are expressed by eosinophils and mast cells. This chemokine has been shown to suppress rapid proliferation of myeloid progenitor cells.
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Synonyms |
CKb12 Protein(Human); HCC-4 Protein(Human); ILINCK Protein(Human); LCC-1 Protein(Human); LEC Protein(Human); LMC Protein(Human); Mtn-1 Protein(Human); NCC-4 Protein(Human); NCC4 Protein(Human); SCYA16 Protein(Human); SCYL4 Protein(Human)
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Images |
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Quantity |
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Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
1 | Leading Biology | PH0003E1 | Recombinant Human TNF Alpha Protein | 10ug | Cytokine |
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$195.00 | Add Ask | ||
2 | Leading Biology | PH0001E2 | Recombinant Human IL-6 Protein | 10ug | Cytokine |
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$195.00 | Add Ask | ||
3 | Leading Biology | PH0073E2 | Recombinant Human CXCL2 Protein | 20μg | Cytokine |
|
$325.00 | Add Ask | ||
4 | Leading Biology | PH0024E3 | Recombinant Human IL-16 Protein (N-His Tag) | 20μg | Cytokine |
|
$325.00 | Add Ask | ||
5 | Leading Biology | PH0045E2 | Recombinant Human IL-37 Protein | 20μg | Cytokine |
|
$325.00 | Add Ask | ||
6 | Leading Biology | PH0041M1 | Recombinant Human IL-34 Protein (C-His Tag) | 20μg | Cytokine |
|
$325.00 | Add Ask |
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