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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Human CCL11 Protein(N-His Tag)

Recombinant Human CCL11 Protein(N-His Tag)

PH0061E3
Catalog # Availability Size / Price Inquiry
PH0061E3-20μg 20μg / $325
PH0061E3-100μg 100μg / $955

Recombinant Human CCL11 Protein(N-His Tag)

Brand

Leading Biology

Catalog Number

PH0061E3

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

E.coli

Species

Human

AA Sequence

P51671(Gly 24-Pro 97)

Tags

N-His

Molecular Weight

14KD

Activity

Measured by its ability to chemoattract BaF3 mouse pro?B cells transfected with mouse CCR3.

Form

lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered PBS, 10 % glycerol, pH7.5

Product Description

CCL11 is a small cytokine belonging to the CC chemokine family. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2,CCR3 and CCR5. However, it has been found that eotaxin-1 (CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.

Synonyms

SCYA11 Protein(Human)

Images

Quantity

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