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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Human IL-36α Protein (C-His Tag)

Recombinant Human IL-36α Protein (C-His Tag)

PH0043E3
Catalog # Availability Size / Price Inquiry
PH0043E3-20μg 20μg / $325
PH0043E3-100μg 100μg / $955

Recombinant Human IL-36α Protein (C-His Tag)

Brand

Leading Biology

Catalog Number

PH0043E3

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

E.coli

Species

Human

AA Sequence

Q9UHA7(Lys 6-Phe158)

Tags

N-His

Molecular Weight

20KD

Activity

Measured by its ability to induce IL-8 secretion in A431 human epithelial carcinoma cells

Form

Lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered PBS, pH7.4

Product Description

Interleukin-36 (IL-36) was first discovered based on its homology to the IL-1 superfamily (IL-1F). IL-36 includes agonist IL. -36α, IL-36β, IL-36γ and inhibitor IL-36Ra, whose agonist mainly has pro-inflammatory function. IL-36Ra acts as a natural inhibitor of IL-36 agonist binding to IL-36R and inhibiting agonist ligands. Binding. IL-36 is biologically active in epithelial cells and specific immune cells. Its functions include cell activation, secretion of cytokines and chemokines, recruitment and activation of different immune cells, etc. Especially in psoriasis. In pathology, IL-36 has a wide range of effects. Recent research data also demonstrate the role of the IL-36 family in the physiology and pathology of the lung.

Synonyms

1E Protein (Human); FIL Protein (Human); FIL1 Protein (Human); FIL1E Protein (Human); IL-1F6 Protein (Human); IL1E Protein (Human); IL1F6 Protein (Human); IL36A Protein (Human)

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Quantity

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