> Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Human TNFSF10 ProteinBrand |
Leading Biology | Catalog Number |
PH0148E2 |
Product Type |
Cytokine | Field of Research |
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Nature |
Recombinant Protein
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Expression Host |
E.coli
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Species |
Human
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AA Sequence |
NP_003801.1(Val 114-Gly 281)
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Tags |
Tag-Free
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Molecular Weight |
19KD
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Form |
lyophilized |
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Purity |
Greater than 95% by SDS-PAGE |
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Storage & Stability |
-70°C
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Storage Buffer |
0.2 μm filtered ?40mM Tris, 0.3 M NaCl, pH 7.0
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Product Description |
In the field of cell biology, TNF-related apoptosis-inducing ligand (TRAIL), is a protein functioning as a ligand that induces the process of cell death called apoptosis. TRAIL is a cytokine that is produced and secreted by most normal tissue cells. It causes apoptosis primarily in tumor cells, by binding to certain death receptors. TRAIL and its receptors have been used as the targets of several anti-cancer therapeutics since the mid-1990s, such as Mapatumumab. However, as of 2013, these have not shown significant survival benefit. TRAIL has also been implicated as a pathogenic or protective factor in various pulmonary diseases, particularly pulmonary arterial hypertension. TRAIL has also been designated CD253 (cluster of differentiation 253) and TNFSF10 (tumor necrosis factor (ligand) superfamily, member 10).
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Synonyms |
APO2L Protein(Human); CD253 Protein(Human); TL2 Protein(Human); TRAIL Protein(Human)
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Images |
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Quantity |
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| 5 | Leading Biology | PH0045E2 | Recombinant Human IL-37 Protein | 20μg | Cytokine |
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| 6 | Leading Biology | PH0041M1 | Recombinant Human IL-34 Protein (C-His Tag) | 20μg | Cytokine |
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$325.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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