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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Human TNFRSF10B Protein(C-His Tag)

Recombinant Human TNFRSF10B Protein(C-His Tag)

PH0145M1
Catalog # Availability Size / Price Inquiry
PH0145M1-20μg  In Stock 20μg / $325
PH0145M1-100μg  In Stock 100μg / $955

Recombinant Human TNFRSF10B Protein(C-His Tag)

Brand

Leading Biology

Catalog Number

PH0145M1

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

Mammalian cell

Species

Human

AA Sequence

NP_003833.3(Met 1-Glu 182)

Tags

C-His

Molecular Weight

20KD

Form

lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered PBS, pH7.4

Product Description

Receptor for the cytotoxic ligand TNFSF10/TRAIL . The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.

Synonyms

DR5 / TRAIL R2 Protein(Human); CD262 Protein(Human); DR5 Protein(Human); KILLER Protein(Human); KILLER/DR5 Protein(Human); TRAIL-R2 Protein(Human); TRAILR2 Protein(Human); TRICK2 Protein(Human); TRICK2A Protein(Human); TRICK2B Protein(Human); TRICKB Protein(Human); ZTNFR9 Protein(Human)

Images

Specification

Quantity

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