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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Mouse LIF Protein

Recombinant Mouse LIF Protein

PM0130M2
Catalog # Availability Size / Price Inquiry
PM0130M2-20μg  In Stock 20μg / $325
PM0130M2-100μg  In Stock 100μg / $955

Recombinant Mouse LIF Protein

Brand

Leading Biology

Catalog Number

PM0130M2

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

Mammalian cell

Species

Mouse

AA Sequence

NP_032527.1(Met1-Phe203)

Tags

Tag-Free

Molecular Weight

34KD

Form

lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered PBS, pH7.4

Product Description

Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate.LIF derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to the cytokine include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation. p53 regulated LIF has been shown to facilitate implantation in the mouse model and possibly in humans. It has been suggested that recombinant human LIF might help to improve the implantation rate in women with unexplained infertility.

Synonyms

CDF Protein(Mouse); DIA Protein(Mouse); HILDA Protein(Mouse); Leukemia Inhibitory Factor Protein(Mouse); MLPLI Protein(Mouse)

Quantity

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