> Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Human HGF ProteinBrand |
Leading Biology | Catalog Number |
PH0114M2 |
Product Type |
Cytokine | Field of Research |
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Nature |
Recombinant Protein
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Expression Host |
Mammalian cell
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Species |
Human
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AA Sequence |
NP_000592.3(Met 1-Ser 728)
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Tags |
Tag-Free
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Molecular Weight |
80KD
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Form |
lyophilized |
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Purity |
Greater than 95% by SDS-PAGE |
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Storage & Stability |
-70°C
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Storage Buffer |
0.2 μm filtered PBS, pH7.4
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Product Description |
Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells and targets and acts primarily upon epithelial cells and endothelial cells, but also acts on haemopoietic progenitor cells and T cells. It has been shown to have a major role in embryonic organ development, specifically in myogenesis, in adult organ regeneration, and in wound healing. Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration.
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Synonyms |
DFNB39 Protein(Human); F-TCF Protein(Human); F-TCFB Protein(Human); Hepatocyte Growth Factor Protein(Human); HGFB Protein(Human); HPTA Protein(Human); SF Protein(Human)
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Images |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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