>
Proteins, Peptides & Amino Acids >
Recombinant Protein >
Cytokine >
Recombinant Human CXCL1 ProteinBrand |
Leading Biology | Catalog Number |
PH0072E2 |
Product Type |
Cytokine | Field of Research |
|
Nature |
Recombinant Protein
|
||
Expression Host |
E.coli
|
||
Species |
Human
|
||
AA Sequence |
P09341-1(Ala35-Asn107)
|
||
Tags |
Tag-Free
|
||
Molecular Weight |
10KD
|
||
Activity |
Measured by its ability to induce myeloperoxidase release from cytochalasin B-treated human neutrophils.
|
||
Form |
lyophilized |
||
Purity |
Greater than 95% by SDS-PAGE |
||
Storage & Stability |
-70°C
|
||
Storage Buffer |
0.2 μm filtered PBS, pH7.4
|
||
Product Description |
The chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MGSA-α). In humans, this protein is encoded by the Cxcl1. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, arteriogenesis, inflammation, wound healing, and tumorigenesis. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines. An initial study in mice showed evidence that CXCL1 decreased the severity of multiple sclerosis and may offer a neuro-protective function.
|
||
Synonyms |
CA21H Protein(Human); CAH1 Protein(Human); CPS1 Protein(Human); CYP21 Protein(Human); CYP21B Protein(Human); FSP Protein(Human); GRO1 Protein(Human); GROa Protein(Human); MGSA Protein(Human); MGSA-a Protein(Human); NAP-3 Protein(Human); P450c21B Protein(Human); SCYB1 Protein(Human)
|
||
Images |
|
||
Quantity |
|
Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
1 | Leading Biology | PH0003E1 | Recombinant Human TNF Alpha Protein | 10ug | Cytokine |
|
$195.00 | Add Ask | ||
2 | Leading Biology | PH0001E2 | Recombinant Human IL-6 Protein | 10ug | Cytokine |
|
$195.00 | Add Ask | ||
3 | Leading Biology | PH0073E2 | Recombinant Human CXCL2 Protein | 20μg | Cytokine |
|
$325.00 | Add Ask | ||
4 | Leading Biology | PH0024E3 | Recombinant Human IL-16 Protein (N-His Tag) | 20μg | Cytokine |
|
$325.00 | Add Ask | ||
5 | Leading Biology | PH0045E2 | Recombinant Human IL-37 Protein | 20μg | Cytokine |
|
$325.00 | Add Ask | ||
6 | Leading Biology | PH0041M1 | Recombinant Human IL-34 Protein (C-His Tag) | 20μg | Cytokine |
|
$325.00 | Add Ask |
Complete this form and click send to ask us a question, request a quote or simply say hello.
You have 0 item in your cart
You have 0 item in your inquiry list