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Recombinant Human CSF-1R Protein(C-His Tag)Brand |
Leading Biology | Catalog Number |
PH0068M1 |
Product Type |
Cytokine | Field of Research |
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Nature |
Recombinant Protein
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Expression Host |
Mammalian cell
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Species |
Human
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AA Sequence |
NP_005202.2(Met 1-Glu512)
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Tags |
C-His
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Molecular Weight |
90KD
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Activity |
Measured by its ability to inhibit the M-CSF-induced proliferation of NFS?60 mouse myelogenous leukemia lymphoblast cells.
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Form |
lyophilized |
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Purity |
Greater than 95% by SDS-PAGE |
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Storage & Stability |
-70°C
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Storage Buffer |
0.2 μm filtered PBS, pH7.4
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Product Description |
Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded, in humans, by the CSF1R gene (known also as c-FMS). It is a receptor for a cytokine called colony stimulating factor 1. The encoded protein is a single pass type I membrane protein and acts as the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most, if not all, of the biological effects of this cytokine. Ligand binding activates CSF1R through a process of oligomerization and trans-phosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases.
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Synonyms |
C-FMS Protein(Human); CD115 Protein(Human); CSF-1R Protein(Human); CSFR Protein(Human); FIM2 Protein(Human); FMS Protein(Human); HDLS Protein(Human); M-CSF-R Protein(Human); MCSF Receptor Protein(Human)
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Images |
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Quantity |
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Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
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$195.00 | Add Ask | ||
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$325.00 | Add Ask | ||
4 | Leading Biology | PH0024E3 | Recombinant Human IL-16 Protein (N-His Tag) | 20μg | Cytokine |
|
$325.00 | Add Ask | ||
5 | Leading Biology | PH0045E2 | Recombinant Human IL-37 Protein | 20μg | Cytokine |
|
$325.00 | Add Ask | ||
6 | Leading Biology | PH0041M1 | Recombinant Human IL-34 Protein (C-His Tag) | 20μg | Cytokine |
|
$325.00 | Add Ask |
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