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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Human CSF-1R Protein(C-His Tag)

Recombinant Human CSF-1R Protein(C-His Tag)

PH0068M1
Catalog # Availability Size / Price Inquiry
PH0068M1-20μg 20μg / $325
PH0068M1-100μg 100μg / $955

Recombinant Human CSF-1R Protein(C-His Tag)

Brand

Leading Biology

Catalog Number

PH0068M1

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

Mammalian cell

Species

Human

AA Sequence

NP_005202.2(Met 1-Glu512)

Tags

C-His

Molecular Weight

90KD

Activity

Measured by its ability to inhibit the M-CSF-induced proliferation of NFS?60 mouse myelogenous leukemia lymphoblast cells.

Form

lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered PBS, pH7.4

Product Description

Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded, in humans, by the CSF1R gene (known also as c-FMS). It is a receptor for a cytokine called colony stimulating factor 1. The encoded protein is a single pass type I membrane protein and acts as the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most, if not all, of the biological effects of this cytokine. Ligand binding activates CSF1R through a process of oligomerization and trans-phosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases.

Synonyms

C-FMS Protein(Human); CD115 Protein(Human); CSF-1R Protein(Human); CSFR Protein(Human); FIM2 Protein(Human); FMS Protein(Human); HDLS Protein(Human); M-CSF-R Protein(Human); MCSF Receptor Protein(Human)

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Quantity

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