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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Mouse IL-12B Protein (C-His Tag)

Recombinant Mouse IL-12B Protein (C-His Tag)

PM0021M1
Catalog # Availability Size / Price Inquiry
PM0021M1-20μg  In Stock 20μg / $325
PM0021M1-100μg  In Stock 100μg / $955

Recombinant Mouse IL-12B Protein (C-His Tag)

Brand

Leading Biology

Catalog Number

PM0021M1

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

Mammalian cell

Species

Mouse

AA Sequence

NP_001290173.1(Met1-Ser335)

Tags

C-His

Molecular Weight

50KD

Activity

Measured in a cell proliferation assay using PHA-stimulated human T lymphoblasts.

Form

Lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered PBS, pH7.4

Product Description

IL-12 can stimulate the proliferation of activated t cells, promote the differentiation of Th0 cells into Th1 cells; induce the cytotoxic activity of CTL and NK cells and promote their secretion of cytokines such as IFN-γ, TNF-α, GM-CSF; The expression of cells and il-2rα, tnf receptor and cd56 molecules enhances the ADCC effect on tumor cells. Due to the important role of IL-12 in anti-tumor immunity and anti-infective immunity, people have high hopes for its clinical application; especially il-12 can cooperate with il-2 to promote the production of ctl and lak cells, indicating that IL-12 and IL- 2 combined use is expected to constitute a more effective method of tumor immunotherapy.

Synonyms

CLMF Protein (Mouse); CLMF2 Protein (Mouse); IL-12B Protein (Mouse); IL12 p40 Protein (Mouse); IMD28 Protein (Mouse); IMD29 Protein (Mouse); NKSF Protein (Mouse); NKSF2 Protein (Mouse)

Images

Quantity

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