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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Human IL-36ɣ Protein

Recombinant Human IL-36ɣ Protein

PH0044E2
Catalog # Availability Size / Price Inquiry
PH0044E2-20μg  In Stock 20μg / $325
PH0044E2-100μg  In Stock 100μg / $955

Recombinant Human IL-36ɣ Protein

Brand

Leading Biology

Catalog Number

PH0044E2

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

E.coli

Species

Human

AA Sequence

Q9NZH8-1(Met 1-Asp 169)

Tags

Tag-Free

Molecular Weight

18KD

Activity

Measured by its ability to induce IL-8 secretion in A431 human epithelial carcinoma cells

Form

Lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered PBS, pH7.4

Product Description

Interleukin-36 (IL-36) was first discovered based on its homology to the IL-1 superfamily (IL-1F). IL-36 includes agonist IL. -36α, IL-36β, IL-36γ and inhibitor IL-36Ra, whose agonist mainly has pro-inflammatory function. IL-36Ra acts as a natural inhibitor of IL-36 agonist binding to IL-36R and inhibiting agonist ligands. Binding. IL-36 is biologically active in epithelial cells and specific immune cells. Its functions include cell activation, secretion of cytokines and chemokines, recruitment and activation of different immune cells, etc. Especially in psoriasis. In pathology, IL-36 has a wide range of effects. Recent research data also demonstrate the role of the IL-36 family in the physiology and pathology of the lung.

Synonyms

IL-1F9 Protein (Human); IL-1H1 Protein (Human); IL-1RP2 Protein (Human);IL-36G Protein (Human)

Images

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