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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Mouse IL-36α Protein

Recombinant Mouse IL-36α Protein

PM0043E2
Catalog # Availability Size / Price Inquiry
PM0043E2-20μg  In Stock 20μg / $325
PM0043E2-100μg  In Stock 100μg / $955

Recombinant Mouse IL-36α Protein

Brand

Leading Biology

Catalog Number

PM0043E2

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

E.coli

Species

Mouse

AA Sequence

Q9JLA2-1(Met 1-His 160)

Tags

Tag-Free

Molecular Weight

20KD

Activity

Measured by its ability to induce IL-8 secretion in A431 human epithelial carcinoma cells

Form

Lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered PBS, pH7.4

Product Description

Interleukin-36 (IL-36) was first discovered based on its homology to the IL-1 superfamily (IL-1F). IL-36 includes agonist IL. -36α, IL-36β, IL-36γ and inhibitor IL-36Ra, whose agonist mainly has pro-inflammatory function. IL-36Ra acts as a natural inhibitor of IL-36 agonist binding to IL-36R and inhibiting agonist ligands. Binding. IL-36 is biologically active in epithelial cells and specific immune cells. Its functions include cell activation, secretion of cytokines and chemokines, recruitment and activation of different immune cells, etc. Especially in psoriasis. In pathology, IL-36 has a wide range of effects. Recent research data also demonstrate the role of the IL-36 family in the physiology and pathology of the lung.

Synonyms

1E Protein (Mouse); FIL Protein (Mouse); FIL1 Protein (Mouse); FIL1E Protein (Mouse); IL-1F6 Protein (Mouse); IL1E Protein (Mouse); IL1F6 Protein (Mouse); IL36A Protein (Mouse)

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Specification

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