STING
Stimulator of interferon genes (STING), also known as transmembrane protein 173 (TMEM173) and MPYS/MITA/ERIS is a protein that in humans is encoded by the TMEM173 gene.
STING plays an important role in innate immunity. STING induces type I interferon production when cells are infected with intracellular pathogens, such as viruses, mycobacteria and intracellular parasites. Type I interferon, mediated by STING, protects infected cells and nearby cells from local infection by binding to the same cell that secretes it (autocrine signaling) and nearby cells (paracrine signaling.)
STING is encoded by the TMEM173 gene. It works as both a direct cytosolic DNA sensor (CDS) and an adaptor protein in Type I interferon signaling through different molecular mechanisms. It has been shown to activate downstream transcription factors STAT6 and IRF3 through TBK1, which are responsible for antiviral response and innate immune response against intracellular pathogen.
| No | Headline | Click | Author | Date |
| 1 | Quality product catalog | 1532 | Leading Biology | 2019-11-20 |
| 2 | Thanksgiving Promotions 2019 | 1512 | Leading Biology | 2019-11-14 |
| 3 | ***BUY 2, GET 1 FREE!*** | 2311 | Leading Biology | 2019-05-13 |
| 4 | New Year Promotion | 2270 | Leading Biology | 2019-01-05 |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
